Chronic Rhinosinusitis: The Mucosal Concept

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Chronic thinosinusitis (CRS) is one of the most common health care complaints, with the prevalence of 5-12% worldwide. This book aims to present the new findings in mechanism, diagnosis and management of this widespread condition to clinical practitioners. All practical information about CRS is compiled; therefore busy clinicians would not have to perform exhaustive literature studies to diagnose CRS.
This book firstly presents the advances in the understanding of epidemiology, genetics, mechanisms, phenotypes, and immunology of this disorder. In the following chapters, details in clinical diagnosis of CRS are summarized, especially clinical characteristics in paediatric CRS. Later chapters introduce medical, surgical, and innovative treatments of CRS, with brief case studies. The role of allergies, asthma, allergic fungal thinosinusitis, and systemic diseases are also discussed. With the illustrative figures, this book is a comprehensive and quick reference to otolaryngologists, paediatricians, family care physicians, allergists, professional clinical staff, and medical students.
Table of Contents
1 Introduction
2 Epidemiology
3 Quality of Life and Psychological Burden
4 Genetics and Epigenetics
5 Involvement of the Immune System in Airways Disease
6 T Cells and Group 2 Innate Lymphoid Cells 2
7 B Cells and Plasma Cells
8 Eosinophils
9 Neutrophils
10 Remodeling Features
11 Nasal Mucociliary Clearance
12 Sinonasal Epithelium
13 Microbiology
14 Staphylococcus aureus and Its Proteins
15 Viruses
16 Environmental and Allergic Triggers
17 Dysfunctional Immune Regulatory System
18 Chronic Rhinosinusitis with and Without Nasal Polyps
19 Allergic Fungal Sinusitis
20 Type 2 Immune Reactions and Consequences
21 Regional Difference
22 Multimorbidities
23 Clinical Diagnosis and Phenotypes
24 Imaging the Anatomic Landmarks for Safe FESS
25 Olfactory Function Assessment
26 Local and Systemic Biomarkers
27 Benign Tumors of the Nose and Sinuses
28 Sinonasal Inverted Papilloma
29 Malignantr fumors of the Nose and Sinuses
30 Pediatric Chronic Rhinosinusitis: View from Europe
31 Pediatric Chronic Sinusitis: View from China
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Chronic Rhinosinusitis: The Mucosal Concept