Animal models showed that once these proteins are cleared from the brain, further damage can be prevented, and existing damage due to a previous stroke can be repaired.

On CT, an iso- to hypodense intraventricular mass will be seen with cystic change and calcification in larger lesions, and associated hydrocephalus if obstructing.

Some children get the stones, because birth defects in the urinary tract put them at risk for urinary obstruction.

Inspection of the abdomen may show distension which is most marked in low obstructions and increases steadily.

The development of obstetric fistula is directly linked to one of the major causes of maternal mortality: obstructed labour.