| 1 | The single mutation in the earwax gene is one in which a G (for guanine) is replaced with an A (for adenine). | |
| 2 | The nucleoside guanosine triphosphate (GTP) is derived from guanine, and supplies energy for certain enzymecatlyzed metabolic reactions. | |
| 3 | It plays an important role in maintaining the intracellular balance of A and G nucleotides. | |
| 4 | In DNA, four different bases are found. Two of these, adenine and guanine, are double-ring structures called purines. | |
| 5 | The high-level requirements of guanine nucleotides and high GTP usage in photoreceptor cells may explain the nature of the retinal degeneration. |
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