1 | A small molecule called an acetyl group attaches to a particular histone known as H4. | |
2 | To reverse the memory loss, doctors inject a compound called a histone deacetylase inhibitor. | |
3 | Histones are proteins that regulate DNA packing, and histone deacetylases are enzymes that control the way those proteins work. | |
4 | It ensures that the H4 histones have plenty of attached acetyl groups, so the DNA wrapped around the histone once again becomes available for transcription. | |
5 | Dr. Fischer' s research shows that when young mice are learning, an acetyl group binds to a particular point on the histone protein. |