| 1 | Another method of sterilization that has been practiced is the use of gaseous ethylene oxide. | |
| 2 | Occluded spores could not be inactivated with ethylene oxide. | |
| 3 | Sterilization by use of ethylene oxide is sometimes attempted for powders. | |
| 4 | However, these were incapable of being inactivated with ethylene oxide as stated previously. | |
| 5 | The manufacturer should validate that the ethylene oxide exposure does, in fact, produce a sterile product. |